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1

2-Alkyl-4-arylimidazoles: Structurally Novel Sodium Channel Modulators.

Anne-Marie Liberatore, Jocelyne Schulz, Jacques Pommier, Marie-Anne Barthelemy, Marion Huchet, Pierre-Etienne Chabrier, Dennis Bigg

Journal:

Year:

2004

File:

PDF, 20 KB

2004

2

Inhibition of nitric oxide synthesis in the forearm arterial bed of patients with advanced cirrhosis

Bernard Campillo, Pierre-Etienne Chabrier, Gabriel Pelle, Said Sediame, Guy Atlan, Paul Fouet, Serge Adnot

Journal:

Year:

1995

Language:

english

File:

PDF, 759 KB

english, 1995

3

2-Alkyl-4-arylimidazoles: structurally novel sodium channel modulators

Anne-Marie Liberatore, Jocelyne Schulz, Jacques Pommier, Marie-Anne Barthelemy, Marion Huchet, Pierre-Etienne Chabrier, Dennis Bigg

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 245 KB

english, 2004

4

Butyl 2-(4-[1.1′-biphenyl]-4-yl-1H-imidazol-2-yl)ethylcarbamate, a potent sodium channel blocker for the treatment of neuropathic pain

Anne-Marie Liberatore, Jocelyne Schulz, Christine Favre-Guilmard, Jacques Pommier, Jacques Lannoy, Emilia Pawlowski, Marie-Anne Barthelemy, Marion Huchet, Michel Auguet, Pierre-Etienne Chabrier, Denni

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 169 KB

english, 2007

5

In Vitro Antioxidant Neuroprotective Activity of BN 80933, a Dual Inhibitor of Neuronal Nitric Oxide Synthase and Lipid Peroxidation

Caroline Demerlé-Pallardy, Véronique Gillard-Roubert, Jean-Grégoire Marin, Michel Auguet, Pierre-Etienne Chabrier

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 422 KB

english, 2000

6

Increased survival and neuroprotective effects of BN82451 in a transgenic mouse model of Huntington's disease

Peter Klivenyi, Robert J. Ferrante, Gabrielle Gardian, Susan Browne, Pierre-Etienne Chabrier, M. Flint Beal

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 34 KB

english, 2003

7

Increased survival and neuroprotective effects of BN82451 in a transgenic mouse model of Huntington's disease

Peter Klivenyi, Robert J. Ferrante, Gabrielle Gardian, Susan Browne, Pierre-Etienne Chabrier, M. Flint Beal

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 758 KB

english, 2003

8

Calpain inhibitors and antioxidants act synergistically to prevent cell necrosis: effects of the novel dual inhibitors (cysteine protease inhibitor and antioxidant) BN 82204 and its pro-drug BN 82270

Bernadette Pignol, Serge Auvin, Denis Carré, Jean-Grégoire Marin, Pierre-Etienne Chabrier

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 250 KB

english, 2006

9

An improved model to investigate the efficacy of antidyskinetic agents in hemiparkinsonian rats

Brigitte Spinnewyn, Christelle Charnet, Sylvie Cornet, Véronique Roubert, Pierre-Etienne Chabrier, Michel Auguet

Journal:

Fundamental & Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 355 KB

english, 2011

10

Synergistic Protective Effects of Antioxidant and Nitric Oxide Synthase Inhibitor in Transient Focal Ischemia

Spinnewyn, Brigitte, Cornet, Sylvie, Auguet, Michel, Chabrier, Pierre-Etienne

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1999

Language:

english

File:

PDF, 417 KB

english, 1999

11

The novel inhibitor of the heterotrimeric G-protein complex, BIM-46187, elicits anti-hyperalgesic properties and synergizes with morphine

Christine Favre-Guilmard, Hamida Zeroual-Hider, Chantal Soulard, Caroline Touvay, Pierre-Etienne Chabrier, Grégoire Prevost, Michel Auguet

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 663 KB

english, 2008

12

Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models

Christine Favre-Guilmard, Michel Auguet, Pierre-Etienne Chabrier

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 848 KB

english, 2009

13

Minimal Effective Dose of Dysport and Botox in a Rat Model of Neurogenic Detrusor Overactivity

Delphine Behr-Roussel, Stéphanie Oger, Bernadette Pignol, Emmanuel Pham, Amélie Le Maux, Pierre-Etienne Chabrier, Stéphanie Caisey, Sandrine Compagnie, Philippe Picaut, Jacques Bernabé, Laurent Alexan

Journal:

European Urology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

14

Long-term treatment with standardized Ginkgo biloba Extract (EGb 761) attenuates cognitive deficits and hippocampal neuron loss in a gerbil model of vascular dementia

Marie-Noelle Rocher, Denis Carré, Brigitte Spinnewyn, Jocelyne Schulz, Sylvie Delaflotte, Bernadette Pignol, Pierre-Etienne Chabrier, Michel Auguet

Journal:

Year:

2011

Language:

english

File:

PDF, 899 KB

english, 2011

15

Differential effects of tyrosine kinase inhibitors on contraction and relaxation of the aortas of normotensive and hypertensive rats

Abdellatif Zerrouk, Michel Auguet, Hubert Dabiré, Anne-Marie Brisac, Michel Safar, Pierre-Etienne Chabrier

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 229 KB

english, 1999

16

Nitric oxide: from basic research to clinical applications

Irene C Green, Pierre-Etienne Chabrier

Journal:

Drug Discovery Today

Year:

1999

Language:

english

File:

PDF, 120 KB

english, 1999

17

Comparison between Endothelial and Neuronal Nitric Oxide Pathways in Rat Aorta and Gastric Fundus

Christine Guilmard, Michel Auguet, Pierre-Etienne Chabrier

Journal:

Year:

1998

Language:

english

File:

PDF, 118 KB

english, 1998

18

Angiotensin II and phorbol-esters potently down-regulate endothelin (ET-1) binding sites in vascular smooth muscle cells

Pierre Roubert, Véronique Gillard, Pascale Plas, Jean-Michel Guillon, Pierre-Etienne Chabrier, Pierre Braquet

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 475 KB

english, 1989

19

Bronchopulmonary and vascular effect of endothelin in the guinea-pig

Caroline Touvay, Béatrice Vilain, Françoise Pons, Pierre-Etienne Chabrier, Jean Michel Mencia-Huerta, Pierre Braquet

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 689 KB

english, 1990

20

Different regulation of vascular tone by angiotensin II and endothelin-1 in rat aorta

Michel Auguet, Sylvie Delaflotte, Jean-Michel Guillon, Pierre-Etienne Chabrier, Pierre Braquet

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 820 KB

english, 1991

21

The vasoconstrictor action of big endothelin-1 is phosphoramidon-sensitive in rabbit saphenous artery, but not in saphenous vein

Michel Auguet, Sylvie Delaflotte, Pierre-Etienne Chabrier, Pierre Braquet

Journal:

European Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 214 KB

english, 1992

22

Different α1-adrenoceptor subtypes mediate contraction in rabbit aorta and urethra

Michel Auguet, Sylvie Delaflotte, Pierre-Etienne Chabrier

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 795 KB

english, 1995

23

Evidence for aggregation of endothelin 1 in water

René Bennes, Bernard Calas, Pierre-Etienne Chabrier, Jacques Demaille, Frédéric Heitz

Journal:

Year:

1990

Language:

english

File:

PDF, 385 KB

english, 1990

24

A novel dual inhibitor of calpains and lipid peroxidation (BN82270) rescues the cochlea from sound trauma

Jing Wang, Bernadette Pignol, Pierre-Etienne Chabrier, Takaomi Saido, Ruth Lloyd, Yong Tang, Marc Lenoir, Jean-Luc Puel

Journal:

Neuropharmacology

Year:

2007

Language:

english

File:

PDF, 2.49 MB

english, 2007

25

BN82451 attenuates l-dopa-induced dyskinesia in 6-OHDA-lesioned rat model of Parkinson’s disease

Brigitte Spinnewyn, Gisele Mautino, Jean-Gregoire Marin, Marie Noëlle Rocher, Anne Sophie Grandoulier, Eric Ferrandis, Michel Auguet, Pierre-Etienne Chabrier

Journal:

Neuropharmacology

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

26

Analgesic effects of Botulinum toxin A in an inflammatory pain model in rats: Comparison of Dysport® and Botox®; synergistic interaction with morphine

Auguet Michel, Favre-Guilmard Christine, Chabrier Pierre-Etienne

Journal:

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

27

Analgesic properties of botulinum toxin type A (Dysport®) in paclitaxel-induced peripheral neuropathy in rats

Favre-Guilmard Christine, Auguet Michel, Chabrier Pierre-Etienne

Journal:

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

28

Absence of implication of L-arginine/nitric oxide pathway on neuronal cell injury induced by L-glutamate or hypoxia

Caroline Demerlé-Pallardy, Marie-Odile Lonchampt, Pierre-Etienne Chabrier, Pierre Braquet

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 3.11 MB

english, 1991

29

Endothelin and Ca++ agonist bay K 8644: Different vasoconstrictive properties

Michel Auguet, Sylvie Delaflotte, Pierre-Etienne Chabrier, Eduardo Pirotzky, François Clostre, Pierre Braquet

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 351 KB

english, 1988

30

Prostacyclin mediates antiaggregatory and hypotensive actions of endothelin in anaesthetized beagle dogs

Ferenc Hermán, Kálmán Magyar, Pierre-Etienne Chabrier, Pierre Braquet, János Filep

Journal:

British Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 368 KB

english, 1989

31

Endothelium independent protective effect of NG-monomethyl-L-arginine on endotoxin-induced alterations of vascular reactivity

Michel Auguet, Jean-Michel Guillon, Sylvie Delaflotte, Eric Etiemble, Pierre-Etienne Chabrier, Pierre Braquet

Journal:

Year:

1991

Language:

english

File:

PDF, 287 KB

english, 1991

32

Nitric oxide synthase induction in glial cells: Effect on neuronal survival

Caroline Demerlé-Pallardy, Marie-Odile Lonchampt, Pierre-Etienne Chabrier, Pierre Braquet

Journal:

Year:

1993

Language:

english

File:

PDF, 491 KB

english, 1993

33

Memory loss in young APPswe/PS1dE9 mice and associated changes in brain metabolism analyzed using a 3D voxel-based approach

Anne-Sophie Hérard, Thierry Delzescaux, Sylvie Cornet, Jessica Lebenberg, Pierre-Etienne Chabrier, Philippe Hantraye, Marc Dhenain

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

34

Memory loss in young APPswe/PS1dE9 mice and associated changes in brain metabolism analyzed using a 3-D voxel-based approach

Anne-Sophie Hérard, Thierry Delzescaux, Sylvie Cornet, Jessica Lebenberg, Pierre-Etienne Chabrier, Philippe Hantraye, Marc Dhenain

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

35

Inhibition of nitric oxide synthesis in the forearm arterial bed of patients with advanced cirrhosis

Bernard Campillo, Pierre-Etienne Chabrier, Gabriel Pelle, Said Sediame, Guy Atlan, Paul Fouet, Serge Adnot

Journal:

Year:

1995

Language:

english

File:

PDF, 741 KB

english, 1995

36

BN 80933, a Dual Inhibitor of Neuronal Nitric Oxide Synthase and Lipid Peroxidation: A Promising Neuroprotective Strategy

Pierre-Etienne Chabrier, Michel Auguet, Brigitte Spinnewyn, Serge Auvin, Sylvie Cornet, Caroline Demerle-Pallardy, Christine Guilmard-Favre, Jean-Gregoire Marin, Bernadette Pignol, Veronique Gillard-R

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.45 MB

english, 1999

37

Characterization of endothelin receptors mediating contraction and relaxation in rabbit saphenous artery and vein

Auguet, Michel, Delaflotte, Sylvie, Chabrier, Pierre-Etienne, Braquet, Pierre

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1993

Language:

english

File:

PDF, 716 KB

english, 1993

38

Involvement of Interleukin-6 and Interferon-α in the Poly(A).Poly(U)-Induced 2',5'-Ohgoadenylate Synthetase Activity in the Mouse Monocyte-Macrophage Cell Line, J774A 1

MARIN, JEAN-GRÉGOIRE, MENCIA-HUERTA, JEAN-MICHEL, BRAQUET, PIERRE, CHABRIER, PIERRE-ETIENNE

Journal:

Journal of Interferon & Cytokine Research

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996

39

Role of Atrial Natriuretic Factor in Impaired Sodium Excretion of Normocapnic and Hypercapnic Patients with Chronic Obstructive Lung Disease

Adnot, Serge, Sediame, Saïd, Defouilloy, Christian, Andrivet, Pierre, Viossat, Isabelle, Brun-Buisson, Christian, Chabrier, Pierre-Etienne, Laurent, Daniel

Journal:

American Review of Respiratory Disease

Year:

1993

Language:

english

File:

PDF, 777 KB

english, 1993

40

Comparison of the Bronchopulmonary and Pressor Activities of Endothelin Isoforms ET-1, ET-2, and ET-3 and Characterization of Their Binding Sites in Guinea Pig Lung

Pons, Francoise, Loquet, Isabelle, Touvay, Caroline, Roubert, Pierre, Chabrier, Pierre-Etienne, Mencia-Huerta, Jean Michel, Braquet, Pierre

Journal:

American Review of Respiratory Disease

Year:

1991

Language:

english

File:

PDF, 810 KB

english, 1991

41

Reversible Inhibition of Inducible, but Not Constitutive, Nitric Oxide Synthase by N G -Nitro-L-Arginine in Rat Aorta

Auguet, Michel, Chabrier, Pierre-Etienne, Braquet, Pierre

Journal:

Year:

1993

Language:

english

File:

PDF, 488 KB

english, 1993

42

Stimulation of the Na+, K+ Pump and the (Na+, K+, Cl-) Cotransport System by Endothelin-1 in Cultured Vascular Smooth Muscle Cells

Garay, Ricardo, Rosati, Clelia, Braquet, Monique, Chabrier, Pierre-Etienne, Braquet, Pierre

Journal:

Journal of Cardiovascular Pharmacology

Year:

1989

File:

PDF, 76 KB

1989

43

Vascular Remodeling and Antihypertensive Therapy

Chabrier, Pierre-Etienne, Esanu, André, Braquet, Pierre

Journal:

Journal of Cardiovascular Pharmacology

Year:

1993

File:

PDF, 2.57 MB

1993

44

Antiaggregatory and Hypotensive Effects of Endothelin-1 in Beagle Dogs

Filep, János G., Hérman, Ferenc, Battistini, Bruno, Chabrier, Pierre-Etienne, Braquet, Pierre, Sirois, Pierre

Journal:

Journal of Cardiovascular Pharmacology

Year:

1991

File:

PDF, 196 KB

1991

45

PD1-03 DOES REDUCTION OF NUMBER OF INTRADETRUSOR INJECTION SITES OF ABOBOTULINUMTOXINA IMPACT EFFICACY AND SAFETY IN A RAT MODEL OF NEUROGENIC DETRUSOR OVERACTIVITY?

Huynh Le Maux, Amélie, Pignol, Bernadette, Behr-Roussel, Delphine, Blachon, Jean-Luc, Chabrier, Pierre-Etienne, Picaut, Philippe, Bernabé, Jacques, Giuliano, Francois, Denys, Pierre

Journal:

The Journal of Urology

Year:

2015

Language:

english

File:

PDF, 48 KB

english, 2015

46

127. Does reduction in number of injection sites of abobotulinumtoxinA impact efficacy in neurogenic detrusor overactivity (NDO) in the spinal cord‒injured (SCI) rat model?

Le Maux, Amélie Huynh, Pignol, Bernadette, Behr-Roussel, Delphine, Blachon, Jean-Luc, Chabrier, Pierre-Etienne, Picaut, Philippe, Bernabé, Jacques, Giuliano, François, Denys, Pierre

Journal:

Year:

2015

Language:

english

File:

PDF, 59 KB

english, 2015

47

Effect of Endothelin-1 on Blood Pressure and Bronchopulmonary System of the Guinea Pig

Braquet, Pierre, Touvay, Caroline, Lagente, Vincent, Vilain, Beatrice, Pons, Francoise, Hosford, David, Chabrier, Pierre-Etienne, Mencia-Huerta, Jean Michel

Journal:

Journal of Cardiovascular Pharmacology

Year:

1989

File:

PDF, 81 KB

1989

48

BN 80933 Inhibits F2-isoprostane elevation in focal cerebral ischaemia and hypoxic neuronal cultures

Marin, Jean-Grégoire, Cornet, Sylvie, Spinnewyn, Brigitte, Demerlé-Pallardy, Caroline, Auguet, Michel, Chabrier, Pierre-Etienne

Journal:

Year:

2000

Language:

english

File:

PDF, 173 KB

english, 2000

49

Stimulation of Na+-H+ exchange, the Na+-K+ pump and Na+,K+,CI- cotransport by endothelin-1 in cultured vascular smooth muscle cells

Rosati, Clelia, Jeanclos, Elisabeth, Nazaret, Corinne, Chabrier, Pierre-Etienne, Hannaert, Patrick, Braquet, Pierre, Garay, Ricardo

Journal:

Journal of Hypertension

Year:

1989

File:

PDF, 186 KB

1989

50

Interaction between atrial natriuretic factor and angiotensin II receptors in the regulation of blood pressure

Chabrier, Pierre-Etienne, Roubert, Pierre, Longchamps, Marie-Odile, Plas, Pascal, Braquet, Pierre

Journal:

Journal of Hypertension

Year:

1988

File:

PDF, 182 KB

1988